Effect of Simvastatin and Antioxidant mix on pulpotomized young permanent teeth: A clinical and radiographic study

Document Type : Original Article

Authors

1 Pedodontics and oral health.faculty of dentistry.Al-azhar university

2 Professor of Pedodontics and Oral Health Faculty of Dental Medicine, Boys, Cairo Al-Azhar University

3 Faculty of Dental Medicine, Boys, Cairo, Al-Azhar University

Abstract

Objective of this study to evaluate, clinically and radiographically, the effect of Simvastatin and Antioxidant mix on pulpotomized young permanent teeth.
Patients & Methods: Pulpotomy were performed in 54 vital decayed young permanent molars that indicated for vital pulp therapy.
The molars were classified randomly into three equal groups
• Group A: molars were receiving Simvastatin after pulpotomy (n=18).
• Group B: molars were receiving Antioxidant mix after pulpotomy(n=18).
• Group C: molars were receiving calcium hydroxide after pulpotomy(n=18).
The treated teeth were followed up clinically and radiographically after variable intervals (immediately, 1 month and 3months) after treatment. The assessment of treated teeth was performed by visual inspection of the signs and symptoms and by periapical radiographs Result: According to pain, mobility and swelling in simvastatin 83.3% of cases was Success and 16.7% of cases was failure. Antioxidant mix 88.9 % of cases was Success and 11.1% of cases was failure. calcium hydroxide,88.9 % of cases was Success and 11.1% of cases was failure. According to Internal or external resorption, widening of periodontal ligament and Periapical radiolucency in simvastatin ,83.3% of cases was Success and16.7% of cases was failure. Antioxidant mix, , 88.9 % of cases was Success and 11.1% of cases was failure. calcium hydroxide , 88.9 % of cases was Success and 11.1% of cases was failure.
Conclusion: simvastatin and Antioxidant mix pulpotomy are more cost, ease in handling, biocompatible. It has been proven potentially to be an ideal pulpotomy materials in treatment of vital young permanent teeth.

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