The effect of alendronate with collagen cone in maintaining of alveolar ridge height and width

Abstract
Objective:
The aim of the study is to evaluate, clinically and radiographically, the effect of alendronate with collagen cone versus collagen cone only in alveolar ridge preservation.
Subjeects and Methods:
32 Patients were selected. All patients had a treatment plan for extraction of non-restorable mandibular molar tooth. Study group (1), the sockets were filled with collagen cone(PARASORB Cone),
Study group (2), the sockets filled with BonApex (alendronate sodium 10 mg), Study group (3), the socket filled with collagen cone in addition to alendronate and Control group (4), the socket left empty and closed. In the present study, the following measurements were recorded: Width of alveolar ridge. Vertical (buccal,lingual and socket bottom) measurements. Bone density.
Results:
Alveolar bone height at the buccal side heights was decrease in all group but more in control group. Collagen+ Alendronate showed the least decrease in lingual height followed by collagen only group. Alveolar bone width was assessed in all groups collagen+ alendronate and collagen only showed the least decrease in width measurements. In this study Collagen+ Alendronate and collagen alone showed the higher increase in bottom measurements. Collagen + Alendronate and collagen only showed the highest increase in density measurements.
Conclusion:
The use of collagen sponge with alendronate in the present study, significantly minimized ridge resorption in all dimensions
Keywords: Collagen , Alendronate , Socket preservation.