Clinical Evaluation Of The Effect Of Tranexamic Acid Mouth Wash On Oral Health Status Of Hemophilic Children

Document Type : Original Article

Authors

1 pedodontics and oral health, faculty of dental medicine alazhar university Egypt cairo

2 Associate professor of Pedodontics and Oral Health Faculty of Dental Medicine, Boys, Cairo Al-Azhar University

3 egypt - cairo - nasr city -69 othman building

4      Professor of Pediatric Hematology, Pediatric Department, National Research Centre.

Abstract

Abstract
Objectives: The present study evaluates the clinical effect of tranexamic acid mouth wash on oral health status of hemophilic children. Subjects and methods: 20 patients with Hemophilia A or B complain from gingivitis were included in the study aged between 5 and 15 years. Control treatment group obtained intravenous factor replacement therapy. Experimental treatment group was instructed to use (TAMW). Results: Spontaneous Bleeding, the median and range of the bleeding episodes was 1(0-8) for CTR and 1(0-12) for ETR with no statistically significant difference between both Sides (p= 0.757). Tooth Brushing Bleeding, the median and range of the bleeding episodes was 2(0-13) for CTR and 4(0-16) for ETR with statistically significant difference between both Sides (p= 0.018). Conclusion: tranexamic acid mouth wash was found to be an effective alternative to FRT in controlling gingival hemorrhage for people with hemophilia undergoing dental scaling. The usage of tranexamic acid wash can help hemophilic children to maintain oral health status by using tooth brushing regularly without fear of gingival bleeding.

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Al-Azhar Journal of Dental Science
Volume 27, Issue 4 - Serial Number 4
October - Pediatric Dentistry & Orthodontics Issue (Pediatric Dentistry, Orthodontics)
October 2024
Pages 579-584

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