Evaluation of Antibiofilm Efficacy of Different Nanoherbal Medications on Multispecies Bacterial Infected Root Canals: An Invitro study

Document Type : Original Article

Authors

1 BDS, 2007G, Al-Azhar University, Demonstrator, Department of Endodontics, Faculty of Dental Medicine, Boys,Cairo, Al-Azhar University

2 Professor of Endodontics, Endodontic Department, Faculty of Dental Medicine, Boys, Cairo, Al Azhar University

3 Assistant Professor of Endodontics, Endodontic Department, Faculty of Dental Medicine, Boys, Cairo, Al Azhar University

Abstract

Background: The main objective of the present study was to evaluate antibiofilm efficacy of different nanoherbal medications on multispecies bacterial infected root canals. Methods: Sixty freshly extracted permanent premolar with vertucci class 1 were collected. According to the type of the herbal applied the samples will be divided into three groups: Group (1) medicated with nano punica granatum herbal extract. Group (2) medicated with nano garlic herbal extract. Group (3) medicated with calcium hydroxide. Group (4) medicated without. The bacteria e. fecalis and staph epidermids were brought according to American tissue culture collection. The teeth samples were sectioned below the cementoenamel junction.. All teeth were then vertically sectioned into two halves. Application of nanoherbals and calcium hydroxide to the samples and incubated for one week. The samples stained and examined under confocal microscope. Results: Negative control showed statistically significantly HIGHER % of live bacteria than the other three groups. Pomegranate showed statistically significantly HIGHER % of dead bacteria than other groups. Conclusion: Pomegranate had a significant antibacterial effect on common oral bacteria. Garlic has great potential in the treatment of many microbial diseases. Nanohaerbals showed better antibacterial effect than herbal extracts.
Al-Azhar Journal of Dental Science
Volume 21, Issue 5 - Serial Number 5
Supplement edition
December 2018
Pages 413-419

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